In concert with other parts of the hippocampal system. Of the hippocampus, and forms part of the foundation for a quantitative theory of how the CA3 operates as an attractor and Part of this evidence is based on the connectivity and associative synaptic plasticity Is involved in spatial function and memory. Part of the evidence that the CA3 is an autoassociation or attractor network comes from data that shows that the hippocampus Provides a quantitative account of the large number of hippocampoвЂ“neocortical back-projections. The concept that the CA1 recodes information fromД¬A3 and sets up associatively learned back-projections to neocortex to allow subsequent retrieval of information to neocortex The perforant path input toД¬A3 is quantitatively appropriate to provide the cue for recall in CA3. Learning (encoding), it has been shown behaviorally that the dentate gyrus supports spatial pattern separation during learning,ДЄnd that the mossy fiber system to CA3 connections are involved in learning but not in recall. Sparse representations by competitive learning and via the mossy fiber pathway forces new representations on the CA3 during Based on the computational proposal that the dentate gyrus produces Implement path integration when the spatial view is obscured. The theory, single neurons in the primate CA3 respond to combinations of spatial view and object, and spatial view and reward.ДЇurthermore, single CA3 neurons reflect the recall of a place from an object in a one-trial object-place event memory task.Д¬A3 neurons also reflect in their firing a memory of spatial view that is retained and updated by idiothetic information to One-trial learning and learning of arbitrary associations and pattern completion where space is a component.

A quantitative computational theory of the operation of the CA3 system as an attractor or autoassociation network is described.Д«ased on the proposal that CA3вЂ“CA3 autoassociative networks are important for episodic or event memory in which space is aД¬omponent (place in rodents and spatial view in primates), it has been shown behaviorally that the CA3 supports spatial rapid

Hippocampus anatomy model network